After searching around more the closest solution I found was using an autohotkey script to send keyboard shortcuts on mouse click and mouse unclick to change between 3d profiles so when you hold down right click it reduces the depth to almost nothing. Im sure its possible to make it actually work the right way with some tinkering with but I dont really have the time to figure out this kinda stuff anymore. more details are here
http://helixmod.blogspot.com/2012/09/borderlands-2-3d-vision-patch.htmlso this works pretty well but if your weapon auto reloads while you're still holding down the ironsight button you will still have the 2d profile enabled until you let go of the button. What would be really interesting to see is this implemented with an RCO so you could use the both eyes open technique.